 |
Analytical Control
Systems, Inc Analytical Control Systems, Inc. |
|
|
317-841-0458
317-841-3186
Analytical Control Systems, Inc.
|
Platelet Aggregation and Platelet Factor 3 Spectra™ APCT versus SPAT™ A study was performed on samples of platelet rich plasma diluted with platelet poor plasma which determined the sensitivity of Spectra™ APCT and SPAT™ to platelet counts.
T he results below document the correlation of the patented Spectra™ Activated Plasma Clotting Time Test with the Slide Platelet Aggregation Test at decreasing levels of platelet rich plasma. The data shows that both tests are sensitive to platelet counts but that the results remain in the normal range for a normal patient up to as low a platelet rich percentage as 6.2. As the concentration of functional platelets is reduced to the point where an adequate quantity to support coagulation is absent, the Slide Platelet Aggregation Test becomes negative. The Spectra™ APCT test gradually lengthens as the level of platelet factor 3 falls. At 6.2 % platelet rich plasma, the Spectra™ APCT time is outside the normal range for the Spectra™ APCT test when used as a screen.
Table 2. Platelet rich plasma was diluted with platelet poor plasma to determine SPAT™'s and Spectra™ APCT's sensitivity to decreasing quantities of platelets.
|
