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Spectra™ APCT, SPAT™ and APTT: How They Work Together

Suggested Coagulation Testing Scheme

Spectra™ APCT, SPAT™ and APTT when used together as a screening package are very effective in detecting abnormalities in the intrinsic system and platelet dysfunction.

 

Spectra™ APCT and SPAT™ were designed to be run together. When combined with the APTT test, they work to efficiently locate potential dysfunction in the intrinsic system and with a patient's platelets. Although it is necessary to fully investigate a coagulation disorder with all tests available to a laboratory, these three can screen for problems and cover a wider range than screening with APTT (& PT) alone.

 

Step 1.

Run APCT

Normal Intrinsic system and platelet factor 3 release normal. With a normal screen it is not always necessary to order a SPAT/ PAA or an APTT.

or

Abnormal Intrinsic system abnormality, platelet problem or testing error present.  Repeat APCT then run APTT and SPAT™ or PAA.

 

Step 2.

Run APTT

Normal Intrinsic system normal. Check platelets by running SPAT™.

or

Abnormal Intrinsic system abnormality, circulating anticoagulant or testing error present.

 

Step 3.

Run SPAT™

Normal Platelet aggregation normal. Check intrinsic factors by running APTT.

or

Abnormal Platelet aggregation abnormality or testing error.   Consider running PAA platelet aggregometery.

 

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